Users describe this bud as having an immediate onset of a light buzzy head high that slowly builds into an energetic, euphoric, and creative head high that leaves them focused and motivated. As they start to come down from the high, a slight tingling is felt in the head and body, leaving you relaxed and at ease. Due to these potent effects, Grapefruit Diesel is an ideal strain for treating patients suffering from conditions such as anxiety, fatigue, depression, and chronic pain due to illness or injury.